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The degreeof pulmonary hypoplasia and the severity of thepulmonary vascular abnormality are the impor-tant issues that determine survival (Bohn et al.1987).

In effect, open canalic-uli are invaginations into the cytoplasm from the plasmamembrane.

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All studies utilized bioassays, and most were performed decades ago whencontemporary bioanalytical technology was not yet available. The SIR will alwaysbe 1 in the standard population, <1 indicates that the rate in one group islower than expected, and >1 that it is higher

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